PMOD Geometric Models and Simulation Tool (PGEM)

Please note that some screenshots show PMOD version 4.3

The PGEM tool supports various types of analyses and simulations based on anatomical data. Particularly, the following tasks are supported:

▪DTI Tractography: Diffusion tensors resulting from the analysis of DWI MR data can be imported and three-dimensional tracts generated. They may be visualized in 3D scenes, used for statistics on the diffusion maps, and exported in vtk format for use in external programs.

▪4D Flow Visualization: MR sequences are able to measure the instantaneous flow vector in vessels over time. In a similar analysis as in tractography, this information can be used for generating streamlines which visualize flow direction and velocity.

▪Generation of Dynamic PET images: Based on an anatomical atlas and a time-activity curve for each atlas structure, a synthetic dynamic PET image can be generated with a certain noise level. Such data can be used for the evaluation of parametric mapping and segmentation approaches.

▪Construction of Vessel Structures and Computational Fluid Dynamics (CFD) simulation: In a first step vessel structures can be segmented from anatomical images and converted into a geometric model. In a second step, flow through the vessel is simulated in an external CFD software. The resulting flows can subsequently be retrieved and analyzed.