PKIN implements different types of models with somewhat different properties.
- Compartment Models require an input curve for the calculation of the expected concentrations in the different compartments. Most of them also support a blood spillover correction term.
- Reference models do not use explicit blood information. Rather, a reference TAC is specified which must satisfy specific criteria. The reference TAC is used to calculate the response in the tissue of interest.
- Non-compartment models perform different types of analyses which are not based on a compartment structure of the model. Most of them use the input curve.
Note: It is assumed that all data used has been decay corrected to the same time point.