PKIN includes some additional models, which are neither explicit compartment nor reference models. They include the important linear regression methods Logan Plot and Patlak Plot, recent alternative methods for estimating the total distribution volume, as well as simple methods to quickly calculate ratios between tissue TACs and/or the plasma concentration.
Model Name 
Description 
Graphical analysis of reversible system to calculate the total distribution volume. 

Reformulation of the Logan plot as a multilinear analysis to reduce noiseinduced bias. Result is the total distribution volume. 

Multilinear analysis derived from the twocompartment model. Results are the total as well as the specific distribution volume. 

Graphical analysis of irreversible system. Applied to FDG studies it allows to estimate glucose turnover. 

Bolus/Infusion 
Based on a bolus study, the bolus/infusion ratio for an equilibrium study can be estimated 
Calculates the integrals of the tissue TAC and the input curve, as well as their ratio. 

Tissue/Plasma 
Calculate the ratio of tissue binding to plasma concentration in order to get an estimate of the total DV 
Calculate the ratio of specific binding to nonspecific binding. 

Calculate the fraction of pased tracer which is accumulated in tissue 

Calculation of the boxcounting dimension of curves 