2-Compartment Model

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2-Compartment Model


The FDG model is a standard 2-tissue compartment model with two additional input parameters, the lumped constant (LC) and the plasma glucose concentration (PG). In combination with the estimated K1, k2, and k3 parameters they allow to calculate the metabolic rate of glucose.

Note: In the FDG model k4 is initially set to 0 assuming metabolic trapping, but can also be fitted.